Formulation and Evaluation of Herbal (Nelumbo Nucifera) Anti-Inflammatory Gel

Abstract

The gel has the safest, easily applicable and most effective due to its directly applicable to the infected part of the skin with minimal adverse effect. This research explores the development and characterization of an anti-inflammatory gel using lotus stem, a plant that has long been valued for its therapeutic qualities, especially its ability to reduce inflammation. Dried ethanolic extract of lotus stem was carefully blended with essential components like Carbopol 934, propylene glycol 400, methylparaben, propylparaben, and distilled water in precisely the right amounts to create the gel formulation. Triethanolamine was gradually added in order to maintain the ideal pH range (6.8–7) for skin compatibility. The developed product was subjected to extensive testing, which included analyses of its physical characteristics, pH, spreadability, viscosity, homogeneity, and potential for skin irritation in animal models. The results highlighted the gel's positive qualities, such as its visually pleasing look, even dispersion, and effective spreadability, indicating bright futures for its use in anti-inflammatory treatment.