Evaluation of Synergistic Potential of Combined Extracts of Apple Peel and Goldenseal Root Extract

Abstract

The study investigates the combined effects of apple peel and goldenseal root extracts as antioxidant and antimicrobial agents. Aqueous and methanolic extracts were found to be the most potent, so two combinations were prepared: methanol combined extracts and aqueous combined extracts. These were used for antioxidant assays such as DPPH radical scavenging, ABTS assay, lipid peroxidation inhibition, and peroxynitrite bleaching of Pyrogallol red. Additionally, antimicrobial assays, including disc diffusion methods, were conducted against various gram-positive and gram-negative bacteria. The study aims to evaluate the synergistic potential of these combined extracts.