Formulation and Assessment of Herbal Toothpaste utilizing extract from Pomegranates, Amla, Alum and Clove Oil

Authors

  • Baibhaw Kumar School of Health Sciences, Department of Pharmacy, Sushant University, Gurugram, Haryana, India
  • Nimish Batra School of Health Sciences, Department of Pharmacy, Sushant University, Gurugram, Haryana, India
  • Deepti Chauhan School of Health Sciences, Department of Pharmacy, Sushant University, Gurugram, Haryana, India
  • Pooja Mehra School of Health Sciences, Department of Pharmacy, Sushant University, Gurugram, Haryana, India

DOI:

https://doi.org/10.62896/ijpdd.1.6.5

Keywords:

Pomegranate extract, Amla extract, Alum, Clove oil, Dental plaque, Antimicrobial, Pain relief, Antibacterial, Antioxidant, oral pathogens

Abstract

The preparation and evaluation of a unique herbal toothpaste using extracts from clove oil (Eugenia caryophyllata), pomegranates (Punica granatum), amla (Phyllanthus emblica), and alum (potassium aluminumsulfate) are shown in this work. Pomegranate peel, amla fruit, alum, and clove oil were used in the formulation process to extract bioactive components, which were then included into a toothpaste base. The toothpaste was subjected to physicochemical characterisation in order to assess variables like stability, viscosity, and pH. Using standardized microbiological assays, the antibacterial activity of the herbal toothpaste was evaluated against common oral pathogens, such as Porphyromonasgingivalis and Streptococcus mutans. Additionally, in vitro and in vivo tests using animal models were used to examine the toothpaste's capacity to prevent plaque formation and lessen gingival irritation. The developed herbal toothpaste outperformed conventional toothpaste controls in terms of antibacterial effectiveness against tested microorganisms, according to the results. It also showed encouraging results in preventing the production of plaque and decreasing gingival irritation, suggesting that it could be a useful dental hygiene solution. Clove oil added to the herbal toothpaste formulation enhanced its analgesic and antibacterial qualities, balancing the effects of alum, amla, and pomegranate extracts. Eugenol, the main component of clove oil, has been demonstrated to have strong antibacterial action against dental pathogens and to relieve gingivitis and toothaches. The herbal toothpaste that has been created using extracts of pomegranates, amla, alum, and clove oil shows promise as a means of improving dental health. Utilizing these natural constituents' synergistic benefits, the toothpaste provides a secure and efficient substitute for traditional oral hygiene solutions. In order to confirm its effectiveness, safety, and long-term advantages for maintaining oral health, more clinical research is necessary.

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Published

2024-05-20

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Section

Articles

How to Cite

Formulation and Assessment of Herbal Toothpaste utilizing extract from Pomegranates, Amla, Alum and Clove Oil. (2024). International Journal of Pharmaceutical Drug Design, 1(6), 40-44. https://doi.org/10.62896/ijpdd.1.6.5

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