A REVIEW ON EMULGEL IN THE TREATMENT TOPICAL APPLICATION

Abstract

The simplest and most straightforward method of delivering localised medications through the skin, ophthalmic, rectal, vaginal, and other routes is topical drug administration. Topical drug delivery methods are those in which a formulation containing an active medicinal ingredient is applied directly to the skin to produce the drug's localising action. Local dermatological problems can be effectively treated with focused medication delivery. Drugs applied to the skin for their local action include antiseptics, antifungal agents, skin emollients, and protectants. This route of drug administration has grown in popularity because it avoids first-pass effects, gastrointestinal irritation, and metabolic degradation associated with oral administration. Emulgel is an emulsion of either the water-in-oil or oil-in-water type that has been gelled by combining with a gelling agent. The fundamental benefit of the emulgel is that it is simple to create emulgel formulations for medications that are lipophilic. Most lipophilic medications cannot be directly synthesized as hydrogels due to solubility issues. Because of this, emulgel offers superior lipophilic drug stability and release than a straightforward hydrogel foundation.