Smart Drug Delivery Solution: Review on Targeted Drug Delivery

Abstract

Smart drug delivery system is an advanced method of drug targeted (dt) delivery. To enhance their therapeutic effects and reduce the related side effects, active drug molecules should selectively accumulate in the disease area for a prolonged period with high controllability. Targeted delivery requires special carrier systems. A tdd carrier is a special molecule, particle, composite, or system that has the ability to hold the drug in or on them, either by encapsulation and / or by means of a separator. Nano-carrier-based tdds have advantages such as higher surface-to-volume ratio, higher and more reactive activity centers, stronger adsorption capacity, and other properties such as morphological preferences. In this various type of targeted drug delivery system. Application of targeted drug delivery is used in diabetic patient, cancer therapy & tissue engineering.

The selection and design of a polymer are challenging tasks because of the inherent diversity of structures and require a thorough understanding of the surface and bulk properties of the polymer that can give the desired chemical, interfacial, mechanical, and biological functions. Natural polymers, e.g., gelatin, collagen, and lecithin, have been widely used in pharmaceuticals for many years. Synthetic polymers have gained a significant attention in recent years due to their wide range of varieties that offer added flexibility in terms of their application in ddss. These are available in a wide variety of composition with readily adjustable properties. Smart drug delivery system various manufacturing method, evaluation parameter can be monitored. In recent advances various marketed example used in targeted drug.